What You Should Know About Disulfiram Implants

downloadDisulfiram (Antabuse) is a drug which acts as useful way to stop further drinking when taken by mouth.

Disulfiram is still the best alternative as a treatment for alcohol dependence. Studies have revealed that patients with alcohol dependence have been treated successfully in a manner that is superior to naltrexone and acamprosate. It is also very useful in those patients who have co-morbid cocaine and alcohol dependence


It is a medicine which is used as a conditioning treatment for alcohol dependence. If taken while consuming alcohol, disulfiram results in many unpleasant effects.


The initial dose can be as 500 mg taken once daily, the dose can be administered in the evening, if the medication is sedating. Ideally the daily dose should be taken in the morning

Side Effects: The side effects of the drug include amongst others generalized flushing, headache, dyspnoea, malaise, vomiting, palpitations, hypotension and tachycardia are also present. Cardiovascular collapse can result in complicated reactions; fatalities have occurred in exceptional instances, this is why their possibility must be explained to the patient before prescribing the drug. However, it is a drug which is not too severe. If however, alcohol is taken a reaction does not ensue it is appropriate to raise the daily dose of disulfiram to 400mg.

It is without alcohol also that the side-effects from disulfiram can develop. If the patient faces serious side effects, it requires the immediate cessation of the drug. These side effects include amongst others convulsions, peripheral neuritis or psychosis; they are rare. Some of the common side-effects are nausea, drowsiness, depression, anorexia, headaches and impotence. Drowsiness is caused when the patient takes the drug at night; a change of medication can be made to citrated calcium carbimide if one of the other effects is persistent (Abstem), in a dose of one or two 50 mg tablets daily.

One of the main difficulties is that of gaining patient compliance with oral deterrents against drinking. Alcoholics who have been asked to take disulfiram may not start the medication; the more frequently stop it prematurely.

Because of the widespread devastating consequences of alcohol abuse many non-pharmaceutical and pharmacological interventions has been developed so as to control alcohol-related problems. An old pharmacological agents used for this purpose is disulfiram.


Its origin dates back to the 1800s, when it was first used in the manufacturing process of rubber. It was in 1937 that the use for containing the effects from alcohol consumption was discovered. This took place when a chemical plant physician by the name of Williams reported the unpleasant symptoms that were seen in the disulfiram-exposed workers after they had consumed alcohol.

How it works

The drug works by creating an acute reaction after alcohol intake. It helps to block the enzyme acetaldehyde dehydrogenase resulting in a metabolic build-up of acetaldehyde thereby resulting in many different kinds of symptoms that are unpleasant after alcohol consumption which is more commonly known as the Disulfiram-Ethanol Reaction (DER). A person cannot bear the physical discomfort. This is when a person experiences these symptoms; most people immediately stop taking alcohol. Despite the fact that it more commonly used treatment alternative, the main concern in coonecti0n with disulfiram therapy is the difficulty of getting patients to take disulfiram on a regular basis. At times the cessation of the drug arises due to the patients intention to resume taking alcohol; in other instances it arises from confidence or apathy that abstention can he maintained by other means. A lot of alcoholics are there who will stop drinking alcohol through measures that do not involve disulfiram or calcium carbimide. However, a deterrent medication is a useful alternative therapy especially in the early stages of abstinence.

How to purchase them

The form of intramuscular implantation or the subcutaneous of sterile pellets of disulfiram is an alternative method of administration. You can get them from the market under the brand name of Esperal.


Treatment for Alcohol Patients – Effects of Alcohol and its Remedies


Alcohol addiction is a very common occurrence. It is the dangerous drinking habit which can harm your relationship and might lead to legal problems. When a person gets addicted to alcohol, he continues to drink even after he know about its harmful effects. The continued drinking of alcohol will lead to depression and you will become dependent on it due to the presence of toxin content in your body. Then your anxiety level increases and you may be infected with cancers. Treatment for alcohol patients begins only when the patient accepts that the problem exists and agrees to stop consuming alcohol. The patient must believe that they will get well soon after the treatment and they must be encouraged and motivated.

The various Treatment for Alcohol Patients is given to overcome the addiction and it is the long process which requires personal dedication and rehabilitations. Its depends on a person’s circumstances, financial situation, and level of support from family and friends. When a person is ready to face the addiction, it is important for them to make the appointment with the doctor. So that the doctors can determine the suitable remedies for them. Unwanted symptoms like the patient may undergo unwanted physical and emotional disturbances. The doctors used to speak with their friends and relatives regarding addiction, symptoms, and treatment opportunities.

Forms of Treatment

Doctors recommend treatment for alcohol patients in various forms. Some of them are,Behaviour Modification:  The process of relearning skills and coping mechanisms is given as the alcohol patients who help them in many situations like when they re-enter environment where they were forced to drink.

Detoxification: Alcohol Patients begin with a detoxification program which helps in breaking the body’s physical addiction to alcohol consumption. This treatment normally conducted in the hospital and takes few weeks to complete as this treatment has strong and powerful physical withdrawal symptoms.

Counselling: In this method of treatment there will be a support group to help the patients to communicate with the individuals and professionals to answer their queries.

Medications: Several medications are also given to the patients like disulfiram, naltrexone, acamprosate, and so on which helps the patient to discontinue their pills.

Home Treatments for Alcohol Addiction

Eating grapes with five hourly intervals can help a person to get rid of consuming alcohol. A person can also have more apples as it reduces the toxin content level in their body. Even though there are many home remedies, Treatment for Alcohol Patients is advisable to get treated by professionals because the doctors and health-care workers have experience in handling the patients and also to manage alcohol withdrawal symptoms. Home treatments for alcohol patients without the supervision of the doctors might lead to risk.


Medicines for Alcohol Users – Suggestions for Using Medications

53abc93583218Alcohol use disorder is the helplessness to control drinking due to physical and emotional addiction to alcohol. The symptoms include continuous alcohol consumption in spite of legal and health issues like drinking alone, drinking in secret, feeling an urge to drink, having more intense if the alcohol is not available, and so on. The Medicines for Alcohol Users helps them in a withdrawal of alcohol to live a healthy life. There are so many problems for the person addicted to alcohol. It will affect him physically, psychologically, and socially. The alcohol will make the person undetected for several years. The alcohol addiction is a gradual process and over time, it can damage the balance of the brain chemical gamma-aminobutyric acid. Also, it may damage glutamate which accelerates the nervous system. When a person consumes alcohol, his brain level of dopamine gets increased and make the drinking habit more satisfying.

There are so many medicines for alcohol users which are FDA-approved medications that help a person in alcohol craving. But these medicines must be used with psychological and social interventions because when they are used in this combination will help the person to reduce the alcohol consumption. It is always better to remember that medications are not a substitute for drinking. It can help make the difference between an alcoholic’s effective and victorious retrieval.

Attacking Alcoholism with Medications

There are approved medicines for alcohol users in the market to treat alcohol addiction. The fact is, all approved medicines are non-additive and can be used alone or in combination with other forms of treatments like behavioural treatments. The behavioural treatments are the method of working with health professionals to identify and change the behaviour that results in heavy drinking. Their functions may include developing the necessary skills needed to stop drinking and building a social support system. Here are the some of the FDA-Approved Medicines for Alcohol Users which help them effectively to avoid drinking.

  • Naltrexone: This medicine helps to reduce the satisfaction of the person gaining from consuming alcohol. Also, it reduces the desire that force them to search out more alcohol. This happens by blocking the receptors in the brain for endorphins and also blocks the proteins that are produced by the body which help to raise temper.
  • Acamprosate: Some Medicines for Alcohol Users are used in the combination with a treatment program. Acamprosate is a medicine used for treating alcohol addiction and to help patients to avoid consuming alcohol. This medicine is used with the combination of a treatment program that involves social support. It works by restoring the balance of certain chemicals in the brain of the patients consuming a large amount of alcohol.

Disulfiram: Always it is advisable to use the disulfiram as directed by the physician as it cause drowsiness. So anyone taking disulfiram must perform other tasks carefully and check with the healthcare provider before start taking it.